CAM Kinase 2 alpha Antibody Cat. No.: 49-389

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Dog, Human, Mouse, Orangutan, Rat
IMMUNOGEN: CAM Kinase 2 alpha antibody was raised against amino acids 6-23 of CAM Kinase 2 alpha (Human).
TESTED APPLICATIONS: ELISA, IF, IHC, WB
APPLICATIONS: CAM Kinase 2 alpha antibody can be used in Western Blot starting at 5 - 10 μg/mL, immunohistochemistry starting at 5 μg/mL, and immunoprecipitation.

psi-iconProperties
PURIFICATION:Purified
CLONALITY:Polyclonal
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
CONCENTRATION:1 mg/ml
STORAGE CONDITIONS:Store CAM Kinase 2 alpha antibody at -20 ˚C prior to opening. Dilute only prior to immediate use. For extended storage aliquot contents and freeze at -20 ˚C or below. As with all antibodies avoid freeze/thaw cycles.

psi-iconAdditional Info
OFFICIAL SYMBOL:CAMK2A
ALTERNATE NAMES:CAMK2A, AlphaCaMKII, CaM-kinase II alpha chain, CaMK-II subunit alpha, CAMKA, CaM kinase II alpha, CaMK II alpha, CaMK-II alpha subunit, CaMKIINalpha, CaM kinase II alpha subunit, CaM kinase II subunit alpha, CaMKII alpha, CaMKIIalpha, KIAA0968
ACCESSION NO.:Q9UQM7
PROTEIN GI NO.:296434552
GENE ID:815
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:CaM Kinase II (also known as CAMK2 and calcium/calmodulin-dependent protein kinase type II alpha chain) is a prominent kinase in the central nervous system that may function in the long-term potentiation of neurotransmitter release. CaM Kinase II autophosphorylates itself at Thr-286 which allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CaM Kinase II is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. This kinase is expressed in brain tissue. Alternative splicing occurs for this gene product.

ANTIBODIES FOR RESEARCH USE ONLY.

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