| HOST SPECIES: | Rabbit |
| SPECIES REACTIVITY: | Human |
| IMMUNOGEN: | C18orf42 antibody was raised against a 16 amino acid peptide from near the center of human C18orf42. The immunogen is located within the last 50 amino acids of C18orf42. |
| TESTED APPLICATIONS: | ELISA, ICC, IF, WB |
| APPLICATIONS: | C18orf42 antibody can be used for the detection of C18orf42 by Western blot at 1 - 2 μg/mL. Antibody can also be used for Immunocytochemistry starting at 2 μg/mL. For immunofluorescence start at 2 μg/mL. Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. |
| SPECIFICITY: | C18orf42 antibody is human specific. |
| POSITIVE CONTROL: | 1) Cat. No. 1201 - HeLa Cell Lysate |
| PREDICTED MOLECULAR WEIGHT: | Predicted: 8 kDa Observed: 12 kDa |
Specifications| PURIFICATION: | C18orf42 Antibody is affinity chromatography purified via peptide column. |
| CLONALITY: | Polyclonal |
| ISOTYPE: | IgG |
| CONJUGATE: | Unconjugated |
| PHYSICAL STATE: | Liquid |
| BUFFER: | C18orf42 Antibody is supplied in PBS containing 0.02% sodium azide. |
| CONCENTRATION: | 1 mg/mL |
| STORAGE CONDITIONS: | C18orf42 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| OFFICIAL SYMBOL: | C18orf42 |
| ALTERNATE NAMES: | Chromosome 18 open reading frame 42 |
| ACCESSION NO.: | NP_001138666 |
| PROTEIN GI NO.: | 223633927 |
| GENE ID: | 642597 |
| USER NOTE: | Optimal dilutions for each application to be determined by the researcher. |
| BACKGROUND: | Little is known of the function of the protein encoded by Chromosome 18 open reading frame 18 (C18orf42), but it is preferentially expressed in neuronal tissue (1). It is thought to bind to the cAMP-dependent protein kinase A (PKA) and regulation its interaction with members of the A-kinase anchoring protein (AKAP) family (1). |
| REFERENCES: | 1) Fukuda M and Aizawa Y. Hypothetical gene C18orf42 encodes a novel protein kinase A-binding protein. Genes Cells 2015; 20:267-80. |
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