BTK Antibody [9D11A9] Cat. No.: 13-186

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psi-iconSpecifications
HOST SPECIES:Mouse
SPECIES REACTIVITY: Human, Mouse
IMMUNOGEN: Recombinant protein of human BTK
TESTED APPLICATIONS: IP, WB
APPLICATIONS: WB: ,1:500 - 1:2000

IP: ,1:20 - 1:50
POSITIVE CONTROL:1) K-562
 2) Raji
 3) THP-1
 4) Mouse spleen
PREDICTED MOLECULAR WEIGHT: Observed: 80kDa

psi-iconProperties
PURIFICATION:Affinity purification
CLONALITY:Monoclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
STORAGE CONDITIONS:Store at -20˚C. Avoid freeze / thaw cycles.

psi-iconAdditional Info
OFFICIAL SYMBOL:BTK
ALTERNATE NAMES:BTK Antibody: AT, ATK, BPK, XLA, IMD1, AGMX1, PSCTK1, Tyrosine-protein kinase BTK, Agammaglobulinemia tyrosine kinase
GENE ID:695
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

ANTIBODIES FOR RESEARCH USE ONLY.

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