BMP6 Antibody Cat. No.: 23-517

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Human, Mouse, Rat
IMMUNOGEN: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human BMP6 (NP_001709.1).
TESTED APPLICATIONS: IF, WB
APPLICATIONS: WB: ,1:500 - 1:2000

IF: ,1:50 - 1:200
POSITIVE CONTROL:1) DU145
 2) Mouse lung
 3) Mouse kidney
 4) Mouse heart
 5) Rat brain
 6) Rat kidney
PREDICTED MOLECULAR WEIGHT: Observed: 57kDa

psi-iconProperties
PURIFICATION:Affinity purification
CLONALITY:Polyclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
STORAGE CONDITIONS:Store at -20˚C. Avoid freeze / thaw cycles.

psi-iconAdditional Info
OFFICIAL SYMBOL:BMP6
ALTERNATE NAMES:BMP6, BMP-6, Bone morphogenetic protein 6, VG-1-related protein, VGR1, VG-1-R, VGR, Vg1, Vg1-related sequence, VGR-1
GENE ID:654
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.

ANTIBODIES FOR RESEARCH USE ONLY.

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