BMP2 Antibody Cat. No.: 13-091

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Human, Mouse, Rat
IMMUNOGEN: Recombinant fusion protein containing a sequence corresponding to amino acids 283-396 of human BMP2 (NP_001191.1).
TESTED APPLICATIONS: IF, IHC, WB
APPLICATIONS: WB: ,1:500 - 1:2000

IHC: ,1:50 - 1:100

IF: ,1:50 - 1:200
POSITIVE CONTROL:1) HeLa
 2) THP-1
 3) PC-12
PREDICTED MOLECULAR WEIGHT: Observed: 45kDa

psi-iconProperties
PURIFICATION:Affinity purification
CLONALITY:Polyclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
STORAGE CONDITIONS:Store at -20˚C. Avoid freeze / thaw cycles.

psi-iconAdditional Info
OFFICIAL SYMBOL:BMP2
ALTERNATE NAMES:BMP2, BDA2, BMP-2, BMP-2A, BMP2A, Bone morphogenetic protein 2, Bone morphogenetic protein 2A
GENE ID:650
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.

ANTIBODIES FOR RESEARCH USE ONLY.

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