BMP-2 Recombinant Protein Cat. No.: 91-010

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psi-iconSpecifications
SPECIES:Human
SOURCE SPECIES:E. coli
SEQUENCE:Gln283-Arg396
FUSION TAG:Tag Free
TESTED APPLICATIONS:
APPLICATIONS:This recombinant protein can be used for biological assays. For research use only.
BIOLOGICAL ACTIVITY: Recombinant BMP-2 is fully biologically active when compared to standards.
ED50 is less than 50 ng/ml as determined by the cytolysis of MC3T3-E1 cells.
Specific Activity of 2.0 x 104 IU/mg
psi-iconProperties
PURITY:Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
PREDICTED MOLECULAR WEIGHT:13.3 kD
PHYSICAL STATE:Lyophilized
BUFFER:Lyophilized from a 0.2 um filtered solution of 50mM HAc . It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 50mM Acetic acid.
STORAGE CONDITIONS:Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
psi-iconAdditional Info
ALTERNATE NAMES:Bone Morphogenetic Protein 2, BMP-2, Bone Morphogenetic Protein 2A, BMP-2A, BMP2, BMP2A
ACCESSION NO.:P12643
PROTEIN GI NO.:189054143
OFFICIAL SYMBOL:BMP2
GENE ID:650
psi-iconBackground and References
BACKGROUND:Bone Morphogenetic Protein-2 (BMP-2) is one of the bone-growth regulatory factors that belong to the transforming growth factor-beta (TGF-beta) superfamily of proteins. BMPs are synthesized as large precursor molecules, which are cleaved by proteolytic enzymes. The active form of BMP-2 can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.

FOR RESEARCH USE ONLY.

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