Inhibition of Indolamine 2, 3 Dioxygenase (IDO) for Cancer Immunotherapy Researchers have found that a drug which inhibits IDO can increase the effectiveness of cancer immunotherapy. Epacadostat, which is an IDO inhibitor, successfully increased the remission… Read More
February 2017: The Antibody Update
Epidermal Levels of Staphylococcus Aureus Are Affected by a Peptide Produced by Other Skin Dwelling Bacteria Staphylococcus aureus is common to many of people’s skin microbiome, and is generally harmless; however, in high population density the… Read More
Problems with Immunotherapy
Pairs of proteins that act as T-cell co-signaling receptors are called immune checkpoints. These cell surface receptors can send positive or negative signals to T cells, instigating a response from the immune system to either… Read More
T-cell Activation: The Purpose of CD28, CTLA-4, and CD80/CD86
A Guide to CD28, CTLA-4, and CD80/CD86 Interaction and Signaling Immune checkpoint receptors like CD28 and CTLA-4 have been of great interest in the research of cancer immunotherapy. These receptors and their ligands are part… Read More
December 2016: The Antibody Update
Merck’s Ebola Vaccine is 100% Effective An extremely effective Ebola virus vaccine created by Merck was recently tested in Guinea with 100% effectiveness. Though the vaccine is late for the worst part of the infection,… Read More
November 2016: The Antibody Update
in China Perform First Injection of CRISPR Modified Cells into a Person Use of CRISPR-Cas9 in human cells for treatment of disease has been a controversial topic amongst scientists since the discovery of the powerful… Read More
October 2016: The Antibody Update
The Nobel Prize in Medicine was Awarded to Yoshinori Ohsumi for His Work on Autophagy Autophagy is the cellular process that regulates a cells ability to degrade parts of itself that must be replaced. Yoshinori Ohsumi’s work… Read More
June 2016: The Antibody Update
First CRISPR/Cas9 Therapeutic Clinical Trials Starting The increasingly popular CRISPR/Cas9 gene editing system has been approved for use in cancer therapy. CRISPR is a DNA sequence that codes for the Cas9 complex, which is able… Read More
March 2016: The Antibody Update
A Possible Vaccine for Dengue Virus Vaccine research has shown that infecting volunteers with a weakened form of the dengue virus is able to boost the immune system enough to prevent future infections. This method of vaccination using… Read More
Lets Make America the Country That Cures Cancer Once and For All
During the 2016 State of the Union Address, President Obama called attention to a myriad of issues currently plaguing Americans. One of the many initiatives President Obama announced in response was a “moonshot” to cure… Read More