Mistakes happen. It’s a fact of life, and when mistakes occur during cell replication, the body has mechanisms to catch these errors and destroy the defective cells. However, when this system fails, it can lead… Read More
February 2017: The Antibody Update
Epidermal Levels of Staphylococcus Aureus Are Affected by a Peptide Produced by Other Skin Dwelling Bacteria Staphylococcus aureus is common to many of people’s skin microbiome, and is generally harmless; however, in high population density the… Read More
Problems with Immunotherapy
Pairs of proteins that act as T-cell co-signaling receptors are called immune checkpoints. These cell surface receptors can send positive or negative signals to T cells, instigating a response from the immune system to either… Read More
January 2017: The Antibody Update
Mitigating the Reproducibility Crisis in Cancer Drug Research Reproducibility has been highlighted as one of the main problems when validating cancer research. Scientists with the The Reproducibility Project have opted to begin pragmatically reviewing the… Read More
T-cell Activation: The Purpose of CD28, CTLA-4, and CD80/CD86
A Guide to CD28, CTLA-4, and CD80/CD86 Interaction and Signaling Immune checkpoint receptors like CD28 and CTLA-4 have been of great interest in the research of cancer immunotherapy. These receptors and their ligands are part… Read More
December 2016: The Antibody Update
Merck’s Ebola Vaccine is 100% Effective An extremely effective Ebola virus vaccine created by Merck was recently tested in Guinea with 100% effectiveness. Though the vaccine is late for the worst part of the infection,… Read More
November 2016: The Antibody Update
in China Perform First Injection of CRISPR Modified Cells into a Person Use of CRISPR-Cas9 in human cells for treatment of disease has been a controversial topic amongst scientists since the discovery of the powerful… Read More
October 2016: The Antibody Update
The Nobel Prize in Medicine was Awarded to Yoshinori Ohsumi for His Work on Autophagy Autophagy is the cellular process that regulates a cells ability to degrade parts of itself that must be replaced. Yoshinori Ohsumi’s work… Read More
August 2016: The Antibody Update
T-cells Run Out of Energy When Fighting in Tumors T-cells were shown to have decreased levels of oxidative metabolism and lower numbers of mitochondria after entering a tumor’s microenvironment. It was shown that T-cells that… Read More
June 2016: The Antibody Update
First CRISPR/Cas9 Therapeutic Clinical Trials Starting The increasingly popular CRISPR/Cas9 gene editing system has been approved for use in cancer therapy. CRISPR is a DNA sequence that codes for the Cas9 complex, which is able… Read More