Not too long ago, we published The 5 A’s of Antibodies infographic, which provides a brief explanation of all what goes into the process of generating custom antibodies against specific targets. Our next step is to begin… Read More
A Brief Introduction to PD-1 Antibodies and Immunotherapy
President Jimmy Carter’s cancer remission was wonderful news, but as some outlets 1 noted, it is important to understand that not all patients are responding as well to similar treatments, and that there is currently still no… Read More
January 2016: The Antibody Update
Multiple Sclerosis Antibody May Be Linked to JC Virus InfectionMultiple sclerosis patients taking Natalizumab showed an increase in the number of cases of the neurodegenerative John Cunningham virus (JCV). JCV can cause a fatal brain… Read More
December 2015: The Antibody Update
Antibody Engineering and Therapeutics Conference Highlights The Antibody Engineering and Therapeutics conference held in San Diego was a fantastic exchange of knowledge between all the participants. One of the many topics that stuck out was… Read More
November 2015: The Antibody Update
Bacteria with Resistance to Polymyxins, the Last Form of Antibiotics, Have Been Found in China Strains of E. coli that are resistant to polymyxin class antibiotics have been found in both pigs and citizens in China. Polymyxins were the… Read More
Tips for Understanding the Reproducibility Crisis
An article published by Nature earlier this year pointed out that researchers now have to worry about the reproducibility of production antibodies. The fact of the matter is that off-the-shelf antibodies from large distributors can be… Read More
ProScis 5 As of Antibody Development Infographic
Antibody development is multi-faceted process that begins with the target to which you wish to develop antibodies against: the antigen. To elicit an immune response we must select the appropriate adjuvant to be mixed with the antigen… Read More
October 2015: The Antibody Update
Antibody Against an Alzheimer’s Associate Protein Presented at the 2015 Society for Neuroscience Conference At the Society for Neuroscience (SfN) conference in Chicago, an abstract was presented by a Harvard research team about an antibody to… Read More
Antibody Basics: Hybridoma
Hybridoma Development Hybridoma technology is the core technique used to develop monoclonal antibodies at ProSci. A hybridoma is a single cell that consists of a cancerous myeloma cell and an immune B-cell which have been fused together… Read More
September 2015: The Antibody Update
New Antibody Targets HIV Glycoprotein at Different Conformations Caltech has discovered a broadly neutralizing antibody (bNAb) that can bind to both partially open and closed conformation of the HIV-1 envelope glycoprotein. Typically bNAbs only target the HIV-1 envelope… Read More