N Engl J Med reported the durability of immunity response of SARS-CoV-2 vaccine, mRNA-1273 (Moderna). The data was from 34 healthy adults with two vaccine injections. They have performed RBD binding assay and antibody neutralization… Read More
ProSci Incorporated’s ACE2 Antibody Published in Cell: ACE2 Rabbit Polyclonal Antibody for Western Blotting
Cell Paper: Genome-wide CRISPR Screen Reveal Host Factors Critical for SARS-CoV-2 Infection COVID-19 (SARS-CoV-2) is a major public health threat with more than 1,200,000 deaths worldwide. The first stage in the coronavirus life cycle is… Read More
SARS-CoV-2 Cleavage
“ What are Proprotein convertases? Proprotein convertases (PC) are comprised of 9 serine secretory proteases that regulate biological processes involved in both healthy and disease states. They are responsible for activating precursor proteins and cell surface… Read More
2019 Novel Coronavirus SARS-COV-2: The Emergence of COVID-19
2019 Novel Coronavirus SARS-COV-2: The Emergence of COVID-19 At the end of 2019, Chinese authorities officially notified the World Health Organization about mysterious pneumonia infections. A week later, scientists identified a novel coronavirus with the full… Read More
The Importance of Quality Reagents In Studying Immune Checkpoint Inhibitors
The Importance of Quality Immuno-oncology Antibody Reagents In Studying Immune Checkpoint Inhibitors These days, it’s tough to mention cancer without also mentioning the novel class of cancer-fighting immuno-oncology therapeutics called immune checkpoint inhibitors. These transformative… Read More
August 2017: The Antibody Update
Zika has run its course for now Herd immunity to Zika virus in American populations is reported to have caused a tremendous decline in the number of cases this year. There was only one reported case in… Read More
How to Detect Single Domain Antibodies
Many scientists expressing interest in single domain antibodies have been curious about the best ways to detect single domain antibodies with in vitro assays. When detecting typical IgG antibodies, secondary antibodies with conjugated enzymes or fluorophores are… Read More
May 2017: The Antibody Update
Inhibition of Indolamine 2, 3 Dioxygenase (IDO) for Cancer Immunotherapy Researchers have found that a drug which inhibits IDO can increase the effectiveness of cancer immunotherapy. Epacadostat, which is an IDO inhibitor, successfully increased the remission… Read More
Why Are Antibodies Produced in the Body?
Antibodies are produced in the body to serve 3 major purposes in the immune system: neutralization, opsonization, and compliment protein activation. Each of these functions helps to protect the body from potentially harmful pathogens. Neutralization… Read More
April 2017: The Antibody Update
Frog-derived Hemagglutinin-Bearing Flu Antiviral An epidermal host defense peptide from the South Indian frog named urumin is virucidal for H1 hemagglutinin-bearing human influenza A viruses. It was demonstrated that this peptide destroyed influenza virions. It… Read More