| SPECIES: | Human |
| SOURCE SPECIES: | HEK293 cells |
| SEQUENCE: | Gln18- Ser740 |
| FUSION TAG: | His-Avi Tag |
| TESTED APPLICATIONS: | ELISA, WB |
| APPLICATIONS: | SDS-PAGE |
Specifications| PURITY: | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
| PREDICTED MOLECULAR WEIGHT: | Predicted: 86.5kD Observed: 95-110kD due to glycosylation |
| PHYSICAL STATE: | Lyophilized |
| BUFFER: | 20mM PB (pH 7.4). 5 % trehalose is added as protectant before lyophilization. |
| STORAGE CONDITIONS: | Store in working aliquots at -20˚C. Avoid freeze/thaw cycles. |
| ALTERNATE NAMES: | Angiotensin-Converting Enzyme 2, ACE-Related Carboxypeptidase, Angiotensin-Converting Enzyme Homolog, ACEH, Metalloprotease MPROT15, ACE2 |
| ACCESSION NO.: | Q9BYF1 |
| BACKGROUND: | ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. |
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