Beta-NGF Recombinant Protein Cat. No.: 40-572

Availability: In stock

$0.00

No Image

 Price Options

* Required Fields

$0.00
psi-iconSpecifications
SPECIES:Human
SOURCE SPECIES:E. coli
SEQUENCE:SSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVR
TESTED APPLICATIONS:
BIOLOGICAL ACTIVITY: Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells. The expected ED50 is ≤ 1.0 ng/mL, corresponding to a specific activity of ≥ 1 x 106 units/mg.
psi-iconProperties
PURITY:Greater than 98% by SDS-PAGE gel and HPLC analyses.
PHYSICAL STATE:Lyophilized
STORAGE CONDITIONS:The lyophilized Beta-NGF recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted Beta-NGF stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing Beta-NGF recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
psi-iconAdditional Info
ALTERNATE NAMES:NGFB, HSAN5, Beta-NGF, NGFB, Beta-nerve growth factor
ACCESSION NO.:NP_002497.2
PROTEIN GI NO.:70995319
OFFICIAL SYMBOL:NGF
GENE ID:4803
psi-iconBackground and References
BACKGROUND:β-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. β-NGF is a potent neurotrophic factor that signals through its receptor β-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. β-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. The functional form of Recombinant Human β-NGF is a non-covalently-linked homodimer of two 13.5 kDa, polypeptide monomers that each contain 120 amino acids and three disulfide bonds, which are required for biological activity.

FOR RESEARCH USE ONLY.

For additional information, visit ProSci's Terms & Conditions Page.