BAFF Recombinant Protein Cat. No.: 40-305

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psi-iconSpecifications
SPECIES:Human
SOURCE SPECIES:E. coli
SEQUENCE:MAVQGPEETV TQDCLQLIAD SETPTIQKGS YTFVPWLLSF KRGSALEEKE NKILVKETGY FFIYGQVLYT DKTYAMGHLI QRKKVHVFGD ELSLVTLFRC IQNMPETLPN NSCYSAGIAK LEEGDELQLA IPRENAQISL DGDVTFFGAL KLL
TESTED APPLICATIONS:
BIOLOGICAL ACTIVITY: Biological activity was determined by a mouse splenocyte survival assay. The expected ED50 for this effect is 0.5 - 2.0 μg/mL.
psi-iconProperties
PURITY:Greater than 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
PHYSICAL STATE:Lyophilized
STORAGE CONDITIONS:The lyophilized BAFF recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted BAFF is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing BAFF recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
psi-iconAdditional Info
ALTERNATE NAMES:DTL, BAFF, BLYS, CD257, TALL1, THANK, ZTNF4, TALL-1, TNFSF20, UNQ401/PRO738, Tumor necrosis factor ligand superfamily member 13B, B lymphocyte stimulator, BLyS
ACCESSION NO.:NP_001139117.1
PROTEIN GI NO.:224548983
OFFICIAL SYMBOL:TNFSF13B
GENE ID:10673
psi-iconBackground and References
BACKGROUND:BAFF, a member of the TNF family of ligands, is expressed in T cells, macrophages, monocytes and dendritic cells. BAFF is involved in stimulation of B and T cell function, and is an important survival and maturation factor for peripheral B cells. BAFF signals through three different TNF receptors TACI, BCMA and BAFF-R. The human BAFF gene codes for a 285 amino acid type II transmembrane protein containing a 46 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 218 amino acid extracellular domain. Recombinant human soluble BAFF is a 153 amino acid polypeptide (17.0 kDa), which contains the TNF-like portion of the extracellular domain of BAFF.

FOR RESEARCH USE ONLY.

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