BAFF Receptor Recombinant Protein Cat. No.: 40-306

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psi-iconSpecifications
SPECIES:Human
SOURCE SPECIES:E. coli
SEQUENCE:MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPG
TESTED APPLICATIONS:
BIOLOGICAL ACTIVITY: Biological activity was determined by its ability to block BAFF induced mouse splenocyte survival. The expected ED50 for this effect is 2.0 - 4.0 μg/mL in the presence of 1.0μg/mL of human soluble BAFF.
psi-iconProperties
PURITY:Greater than 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
PHYSICAL STATE:Lyophilized
STORAGE CONDITIONS:The lyophilized BAFF Receptor recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted BAFF Receptor is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing BAFF Receptor recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
psi-iconAdditional Info
ALTERNATE NAMES:BAFFR, CD268, CVID4, BAFF-R, BROMIX, prolixin, BAFFR, BR3, Tumor necrosis factor receptor superfamily member 13C, B-cell-activating factor receptor
ACCESSION NO.:NP_443177.1
PROTEIN GI NO.:16445027
OFFICIAL SYMBOL:TNFRSF13C
GENE ID:115650
psi-iconBackground and References
BACKGROUND:BAFF Receptor (BAFFR), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFFR is a type III transmembrane protein that binds with high specificity to BAFF (TNFSF13B). BAFFR/BAFF signaling plays a critical role in B cell survival and maturation. Recombinant human BAFFR is a 76 amino acid polypeptide (7.7 kDa) corresponding to the extracellular portion of the full BAFFR protein.

FOR RESEARCH USE ONLY.

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