BAFF Antibody [4.62] (biotin) Cat. No.: 36-120

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psi-iconSpecifications
HOST SPECIES:Rat
SPECIES REACTIVITY: Human
IMMUNOGEN: HA-tagged human BAFF.
TESTED APPLICATIONS: ELISA, Func, IP
APPLICATIONS: ELISA: (as a detection antibody). Functional Application: Inhibition of human BAFF binding. Immunoprecipitation: (1:200).
SPECIFICITY: Recognizes human BAFF.

psi-iconProperties
PURIFICATION:>95% (SDS-PAGE)
CLONALITY:Monoclonal
ISOTYPE:IgG2a
CONJUGATE:Biotin
PHYSICAL STATE:Liquid
BUFFER:Liquid. In PBS containing 0.02% sodium azide.
CONCENTRATION:0.5 mg/ml
STORAGE CONDITIONS:Stable for at least 1 year after receipt when stored at -20˚C.

psi-iconAdditional Info
OFFICIAL SYMBOL:TNFSF13B
ALTERNATE NAMES:BLyS; TALL-1; CD257; B Cell Activating Factor; TNFSF13B
ACCESSION NO.:5730097
PROTEIN GI NO.:NP_006564
GENE ID:10673
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren’s syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).

ANTIBODIES FOR RESEARCH USE ONLY.

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