BAFF and Receptor Detection Set Cat. No.: PSI-1803

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psi-iconSpecifications
SPECIES REACTIVITY:Human
TESTED APPLICATIONS:IF, IHC, WB
APPLICATIONS:These polyclonal antibodies can be used for detection of BAFF and its receptors by Western blot at 2 μg/mL to 1 μg/mL, Immunohistochemistry, and Immunoflourescence. Whole cell lysate from HepG2 cells can be used as a positive control for each antibody except BAFF-R antibody; murine spleen lysate can be used as a positive control for that.
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
IMMUNOGEN:Rabbit polyclonal antibodies were raised against peptides corresponding to amino acid sequences from each of the corresponding proteins.
psi-iconSet Contents
Catalog Number 2221Catalog number 2221 — BAFF Antibody
Catalog Number 2415Catalog number 2415 — APRIL Antibody
Catalog Number 2395Catalog number 2395 — TACI Antibody
Catalog Number 2397Catalog number 2397 — BCMA Antibody
Catalog Number 3097Catalog number 3097 — BAFF Receptor Antibody
psi-iconProperties
PHYSICAL STATE:Liquid
BUFFER:PBS containing 0.02% sodium azide.
CONCENTRATION:Antibody 1 mg/mL
STORAGE CONDITIONS:Stable at 4˚C for three months, store at -20˚C for up to one year.
psi-iconAdditional Info
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground
BACKGROUND:Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members were recently identified by several groups and designated BAFF and APRIL. Both proteins stimulate B cell proliferation, humoral immune responses, NF-κB activation, and apoptosis. Two receptors, TACI and BCMA, recognize both BAFF and APRIL; a third receptor, BAFF-R, is specific for BAFF. These ligands and their receptors are involved in the development of autoimmune diseases as well as cancer.

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