BACE1 Antibody Cat. No.: 48-373

Availability: In stock

$0.00

 Price Options

* Required Fields

$0.00
psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Bat, Bovine, Dog, Gibbon, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
IMMUNOGEN: BACE1 antibody was raised against a peptide located near the internal domain of BACE1 (Human).
TESTED APPLICATIONS: IHC
APPLICATIONS: BACE1 antibody can be used in immunohistochemistry starting at 1:50.
SPECIFICITY: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

psi-iconProperties
PURIFICATION:Immunoaffinity Chromatography
CLONALITY:Polyclonal
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:PBS, 0.1% sodium azide.
CONCENTRATION:1 mg/ml
STORAGE CONDITIONS:BACE1 antibody should be stored long term (months) at -80 ˚C and short term (days) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles.

psi-iconAdditional Info
OFFICIAL SYMBOL:BACE1
ALTERNATE NAMES:BACE1, APP beta-secretase, Asp 2, ASP2, Aspartyl protease 2, Aspartylprotease 2, Beta-secretase, Beta-site APP-cleaving enzyme, BACE, HSPC104, KIAA1149, B-Secretase, Beta-secretase 1, Memapsin-2
ACCESSION NO.:P56817
PROTEIN GI NO.:296434407
GENE ID:23621
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:Bace 1 is responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.

ANTIBODIES FOR RESEARCH USE ONLY.

For additional information, visit ProSci's Terms & Conditions Page.