B7-H5 Recombinant Protein Cat. No.: 97-058

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psi-iconSpecifications
SPECIES:Rhesus monkey
SOURCE SPECIES:HEK293 cells
SEQUENCE:Phe 33 - Thr 192
FUSION TAG:His Tag
TESTED APPLICATIONS:WB
APPLICATIONS:This recombinant protein can be used for WB. For research use only.
psi-iconProperties
PURITY:>95% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.
PREDICTED MOLECULAR WEIGHT:19.9 kDa
PHYSICAL STATE:Lyophilized
BUFFER:PBS, pH7.4
STORAGE CONDITIONS:Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
psi-iconAdditional Info
ALTERNATE NAMES:B7-H5,SISP1,Gi24,VISTA
ACCESSION NO.:NP_001177807.1
OFFICIAL SYMBOL:B7-H5
GENE ID:709595
psi-iconBackground and References
BACKGROUND:Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.
REFERENCES:1) Sakr M.A., et al., 2010, Cancer Sci., 101: 2368-2374.
2) Mayya V., et al ., 2009, Sci. Signal., 2: RA46-RA46.

FOR RESEARCH USE ONLY.

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