Autophagy protein 3 Recombinant Protein Cat. No.: 91-995

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psi-iconSpecifications
SPECIES:Human
SOURCE SPECIES:E. coli
SEQUENCE:Met1-His287
FUSION TAG:C-6 His, N-T7 tag
TESTED APPLICATIONS:
APPLICATIONS:This recombinant protein can be used for biological assays. For research use only.
psi-iconProperties
PURITY:Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
PREDICTED MOLECULAR WEIGHT:35 kD
PHYSICAL STATE:Liquid
BUFFER:Supplied as a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
STORAGE CONDITIONS:Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
psi-iconAdditional Info
ALTERNATE NAMES:Ubiquitin-Like-Conjugating Enzyme ATG3, Autophagy-Related Protein 3, APG3-Like, hApg3, Protein PC3-96, ATG3, APG3, APG3L
ACCESSION NO.:Q9NT62
OFFICIAL SYMBOL:ATG3
GENE ID:64422
psi-iconBackground and References
BACKGROUND:Ubiquitin-Like-Conjugating Enzyme ATG3 (ATG3) is widely expressed and has highly levels in heart, skeletal muscle, kidney, liver and placenta. ATG3 as a E2-like enzyme, involves in autophagy and mitochondrial homeostasis. ATG3 catalyzes the conjugation of ATG8-like proteins to PE which is essential for autophagy. As an autocatalytic E2-like enzyme, ATG3 also can catalyzes the conjugation of ATG12 to itself which palys a role in mitochondrial homeostasis but not in autophagy.

FOR RESEARCH USE ONLY.

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