ASK1 (phospho Ser966) Antibody Cat. No.: 79-187

Availability: In stock

$0.00

 Price Options

$0.00
psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Human, Mouse
IMMUNOGEN: ASK1 (Phospho-Ser966) antibody was raised against a peptide sequence around phosphorylation site of serine 966 (S-I-S (p) -L-P) derived from Human ASK1.
TESTED APPLICATIONS: IHC, WB
APPLICATIONS: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
SPECIFICITY: This antibody detects endogenous level of ASK1 only when phosphorylated at serine 966.
PREDICTED MOLECULAR WEIGHT: 155 kDa

psi-iconProperties
PURIFICATION:Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
CLONALITY:Polyclonal
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
CONCENTRATION:1 mg/mL
STORAGE CONDITIONS:Store antibody at -20˚C for up to one year.

psi-iconAdditional Info
OFFICIAL SYMBOL:MAP3K5
ALTERNATE NAMES:ASK1, MEKK5, MAPKKK5, SRK, ASK-1, M3K5, MAP3K5, MAPK/ERK kinase kinase 5
ACCESSION NO.:NP_005914.1
PROTEIN GI NO.:5174547
GENE ID:4217
psi-iconBackground and References
BACKGROUND:Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death.
REFERENCES:1) Zhang W, et al. (2005) J Biol Chem. 280 (19): 19036-19044. Fujii K, et al. (2004) Oncogene. 23 (29): 5099-5104. Goldman EH, et al. (2004) J Biol Chem 2004 Mar 12; 279 (11): 10442-10449. Zhang L, et al. (1999) Proc Natl Acad Sci U S A. 96 (15): 8511-8515.

ANTIBODIES FOR RESEARCH USE ONLY.

For additional information, visit ProSci's Terms & Conditions Page.