ASK1 (Ab 83) Antibody Cat. No.: 79-329

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Human
IMMUNOGEN: ASK1 (Ab-83) antibody was raised against a peptide sequence around aa.81~85 (G-S-S-V-G) derived from Human ASK1.
TESTED APPLICATIONS: IF, IHC, WB
APPLICATIONS: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
SPECIFICITY: This antibody detects endogenous level of total ASK1 protein.
PREDICTED MOLECULAR WEIGHT: 155 kDa

psi-iconProperties
PURIFICATION:Antibodies were purified by affinity-chromatography using epitope-specific peptide.
CLONALITY:Polyclonal
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
CONCENTRATION:1 mg/mL
STORAGE CONDITIONS:Store antibody at -20˚C for up to one year.

psi-iconAdditional Info
OFFICIAL SYMBOL:MAP3K5
ALTERNATE NAMES:ASK1, MEKK5, MAPKKK5, HER3, ASK-1, M3K5, MAP3K5, MAPK/ERK kinase kinase 5
ACCESSION NO.:NP_005914.1
PROTEIN GI NO.:5174547
GENE ID:4217
psi-iconBackground and References
BACKGROUND:Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death.
REFERENCES:1) Mabuchi S, et al. (2004) Endocrinology. 145 (1): 49-58. Yuan ZQ, et al. (2003) J Biol Chem. 278 (26): 23432-23440. Kim AH, et al. (2001) Mol Cell Biol. 21 (3): 893-901.

ANTIBODIES FOR RESEARCH USE ONLY.

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