ASIP Antibody Cat. No.: 22-520

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Mouse, Rat
IMMUNOGEN: Recombinant fusion protein containing a sequence corresponding to amino acids 23-132 of human ASIP (NP_001663.2).
TESTED APPLICATIONS: IF, IHC
APPLICATIONS: IHC: ,1:50 - 1:100

IF: ,1:50 - 1:100

psi-iconProperties
PURIFICATION:Affinity purification
CLONALITY:Polyclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
STORAGE CONDITIONS:Store at -20˚C. Avoid freeze / thaw cycles.

psi-iconAdditional Info
OFFICIAL SYMBOL:ASIP
ALTERNATE NAMES:AGSW, AGTI, AGTIL, ASP, SHEP9, agouti-signaling protein, agouti signaling protein, nonagouti homolog, agouti switch protein, nonagouti homolog
GENE ID:434
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes.

ANTIBODIES FOR RESEARCH USE ONLY.

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