| SPECIES: | Human |
| SOURCE SPECIES: | Human Cells |
| SEQUENCE: | Arg19-Ala507 |
| FUSION TAG: | C-6 His tag |
| TESTED APPLICATIONS: | |
| APPLICATIONS: | This recombinant protein can be used for biological assays. For research use only. |
Specifications| PURITY: | Greater than 95% as determined by reducing SDS-PAGE. Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test. |
| PREDICTED MOLECULAR WEIGHT: | 52.9 kD |
| PHYSICAL STATE: | Liquid |
| BUFFER: | Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, pH 7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml. |
| STORAGE CONDITIONS: | Store at -20˚C, stable for 6 months after receipt. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| ALTERNATE NAMES: | Arylsulfatase A, ASA, Cerebroside-Sulfatase, ARSA |
| ACCESSION NO.: | P15289 |
| OFFICIAL SYMBOL: | ARSA |
| GENE ID: | 410 |
| BACKGROUND: | Arylsulfatase A (ARSA) is a lysosomal enzyme that breaks down Cerebroside 3-Sulfate, a major constituent of the myelin sheet, into Cerebroside and Sulfate. The ARSA deficiency results in Metachromatic Leukodystrophy (MLD), a lysosomal storage disease in the central and peripheral nervous systems with severe and progressive neurological symptoms. Recombinant Human ARSA corresponds to the ARSA mature peptide and has sulfatase activity. |
FOR RESEARCH USE ONLY.
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