ARNTL2 Antibody Cat. No.: 25-508

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Human
IMMUNOGEN: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ARNTL2.
TESTED APPLICATIONS: ELISA, WB
APPLICATIONS: ARNTL2 antibody can be used for detection of ARNTL2 by ELISA at 1:1562500. ARNTL2 antibody can be used for detection of ARNTL2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
POSITIVE CONTROL:1) Cat. No. 1219 - MCF7 Cell Lysate
PREDICTED MOLECULAR WEIGHT: 71 kDa

psi-iconProperties
PURIFICATION:Antibody is purified by peptide affinity chromatography method.
CLONALITY:Polyclonal
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
CONCENTRATION:batch dependent
STORAGE CONDITIONS:For short periods of storage (days) store at 4˚C. For longer periods of storage, store ARNTL2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

psi-iconAdditional Info
OFFICIAL SYMBOL:ARNTL2
ALTERNATE NAMES:ARNTL2, BMAL2, CLIF, MGC149671, MGC149672, MOP9, PASD9, bHLHe6
ACCESSION NO.:NP_064568
PROTEIN GI NO.:31745180
GENE ID:56938
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:ARNTL2-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription. Also, in umbilical vein endothelial cells, ARNTL2 activates SERPINE1 through E-box sites. This transactivation is inhibited by PER2 and CRY1.
REFERENCES:1) Shi, J., (er) Am. J. Med. Genet. B Neuropsychiatr. Genet. (2008) In press.

ANTIBODIES FOR RESEARCH USE ONLY.

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