AOF2 Antibody Cat. No.: 49-261

Availability: In stock

$0.00

 Price Options

$0.00
psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Dog, Human, Macaque, Monkey, Mouse, Rat, Zebrafish
IMMUNOGEN: A portion of amino acids 100-150 of human LSD1.
TESTED APPLICATIONS: IHC, WB
APPLICATIONS: AOF2 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 5 μg/mL.
SPECIFICITY: The amino acid sequence used as immunogen is 100% homologous in human (isoform b), mouse, rat, dog, zebrafish and rhesus monkey.

psi-iconProperties
PURIFICATION:Immunoaffinity Chromatography
CLONALITY:Polyclonal
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:PBS, 0.2% gelatin, 0.05% sodium azide.
CONCENTRATION:0.5 mg/ml
STORAGE CONDITIONS:Store AOF2 antibody at 4 ˚C for short term applications. For long term storage, aliquot and -20 ˚C.

psi-iconAdditional Info
OFFICIAL SYMBOL:KDM1A
ALTERNATE NAMES:KDM1A, BHC110, KDM1, LSD1, AOF2, KIAA0601
ACCESSION NO.:O60341
PROTEIN GI NO.:51315808
GENE ID:23028
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:LSD1 is a flavin-containing novel nuclear protein having an N-terminal SWIRM domain and a C-terminal FAD-binding motif and an amine oxidase domain. It functions as a transcriptional corepressor and catalyzes the flavin-dependant demethylation of Lys4 of histone3 resulting in the formation of methyl-free lysine and release of formaldehyde. LSD1 has been found to be typically associated with CoREST and histone deacetylases 1 and 4 and participates in the silencing of endogenous neuron-specific genes.

ANTIBODIES FOR RESEARCH USE ONLY.

For additional information, visit ProSci's Terms & Conditions Page.