This recombinant proteins is for research use only.
BIOLOGICAL ACTIVITY:
N/A
Properties
PURITY:
>95% (SDS-PAGE)
PHYSICAL STATE:
Liquid
BUFFER:
In PBS, pH 7.4, containing 0.02% sodium azide.
STORAGE CONDITIONS:
Stable for at least 1 year after receipt when stored at +4˚C.
Additional Info
ALTERNATE NAMES:
Annexin A5, Endonexin II, Lipocortin V, Placental Anticoagulant Protein I, Calphobindin I, Vascular Anticoagulant-alpha
ACCESSION NO.:
P08758
PROTEIN GI NO.:
113960
OFFICIAL SYMBOL:
ANXA5
GENE ID:
308
Background and References
BACKGROUND:
Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e. g. platelets) with prothrombin or coagulation factors and inhibis the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the "annexin V affinity assay" to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.
Specifications
