Annexin V ATTO 647N Recombinant Protein Cat. No.: 90-220

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psi-iconSpecifications
SPECIES:Human
SOURCE SPECIES:E. coli
SEQUENCE:Recombinant human annexin V fused to a GST-tag.
FUSION TAG:GST tag
TESTED APPLICATIONS:
APPLICATIONS:This recombinant proteins is for research use only.
BIOLOGICAL ACTIVITY: N/A
psi-iconProperties
PURITY:>95% (SDS-PAGE)
PHYSICAL STATE:Liquid
BUFFER:In PBS, pH 7.4, containing 0.02% sodium azide.
STORAGE CONDITIONS:Stable for at least 1 year after receipt when stored at +4˚C.
psi-iconAdditional Info
ALTERNATE NAMES:Annexin A5, Endonexin II, Lipocortin V, Placental Anticoagulant Protein I, Calphobindin I, Vascular Anticoagulant-alpha
ACCESSION NO.:P08758
PROTEIN GI NO.:113960
OFFICIAL SYMBOL:ANXA5
GENE ID:308
psi-iconBackground and References
BACKGROUND:Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e. g. platelets) with prothrombin or coagulation factors and inhibis the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the "annexin V affinity assay" to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.

FOR RESEARCH USE ONLY.

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