Specifications
| HOST SPECIES: | Rabbit |
| SPECIES REACTIVITY: |
Human, Mouse |
| IMMUNOGEN: |
Recombinant fusion protein containing a sequence corresponding to amino acids 26-406 of human ANGPTL4 (NP_647475.1). |
| TESTED APPLICATIONS: |
IF, WB |
| APPLICATIONS: |
WB: ,1:500 - 1:2000
IF: ,1:50 - 1:200 |
| POSITIVE CONTROL: | 1) NCI-H460 |
| | 2) 293T |
| | 3) SH-SY5Y |
| PREDICTED MOLECULAR WEIGHT: |
Observed: 44kDa |
Properties
| PURIFICATION: | Affinity purification |
| CLONALITY: | Polyclonal |
| ISOTYPE: | IgG |
| CONJUGATE: | Unconjugated |
| PHYSICAL STATE: | Liquid |
| BUFFER: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| STORAGE CONDITIONS: | Store at -20˚C. Avoid freeze / thaw cycles. |
Additional Info
| OFFICIAL SYMBOL: | ANGPTL4 |
| ALTERNATE NAMES: | Angiopoietin-like Protein 4; FIAF; Fasting-induced Adipose Factor; HFARP; Hepatic Fibrinogen/Angiopoietin-related Protein |
| GENE ID: | 51129 |
| USER NOTE: | Optimal dilutions for each application to be determined by the researcher. |
Background and References
| BACKGROUND: | This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. |
ANTIBODIES FOR RESEARCH USE ONLY.
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