ANGPTL4 (166-406) Recombinant Protein Cat. No.: 96-028

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psi-iconSpecifications
SPECIES:Human
SOURCE SPECIES:HEK293 cells
SEQUENCE:Pro 166 - Ser 406
FUSION TAG:N-His Tag
TESTED APPLICATIONS:WB
APPLICATIONS:This recombinant protein can be used for WB. For research use only.
psi-iconProperties
PURITY:>95% as determined by SDS-PAGE.
PREDICTED MOLECULAR WEIGHT:27.9 kDa
PHYSICAL STATE:Lyophilized
BUFFER:50 mM MOPS, 100 mM NaCl, pH7.2 with 0.1% CHAPS
STORAGE CONDITIONS:Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
psi-iconAdditional Info
ALTERNATE NAMES:ANGPTL4, ANGPTL2, ARP4, FIAF, HFARP, NL2, PGAR, pp1158, Angiopoietin like 4
ACCESSION NO.:NP_647475
OFFICIAL SYMBOL:ANGPTL4
GENE ID:51129
psi-iconBackground and References
BACKGROUND:Angiopoietin-related protein 4 (ANGPTL4) is also known as Hepatic fibrinogen / angiopoietin - related protein (HFARP), ARP4, PGAR. ANGPTL4 contains one fibrinogen C-terminal domain. ANGPTL4 is a homooligomer , and the homooligomer undergoes proteolytic processing to release its carboxyl fibrinogen-like domain, which circulates as a monomer. The homooligomer unprocessed form is able to interact with the extracellular matrix. ANGPTL4 may act as a regulator of angiogenesis and modulate tumorigenesis. ANGPTL4 inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action.
REFERENCES:1) Yoon J.C., et al., 2000, Mol. Cell. Biol. 20:5343-5349.
2) Ito Y., et al., 2003, Cancer Res. 63:6651-6657.
3) Zhu H., et al., 2002, Zhonghua Zhong Liu Za Zhi 24:123-125.

FOR RESEARCH USE ONLY.

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