ALCAM Recombinant Protein Cat. No.: 96-124

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psi-iconSpecifications
SPECIES:Human
SOURCE SPECIES:HEK293 cells
SEQUENCE:Trp 28 - Ala 526
FUSION TAG:His Tag
TESTED APPLICATIONS:WB
APPLICATIONS:This recombinant protein can be used for WB. For research use only.
BIOLOGICAL ACTIVITY: Measured by its binding ability in a functional ELISA. Immobilized rh CD166 / ALCAM at 10μg/ml (100μl/well) can bind mouse CD6 Fc Chimera, The EC50 of mouse CD6 Fc Chimera is 0. 1-0. 22μg/ml.
psi-iconProperties
PURITY:>95% as determined by SDS-PAGE.
PREDICTED MOLECULAR WEIGHT:57.8 kDa
PHYSICAL STATE:Lyophilized
BUFFER:PBS, pH 7.4
STORAGE CONDITIONS:Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
psi-iconAdditional Info
ALTERNATE NAMES:CD166, ALCAM, CD6L, KG-CAM, MEMD
ACCESSION NO.:Q13740-1
OFFICIAL SYMBOL:ALCAM
GENE ID:214
psi-iconBackground and References
BACKGROUND:CD166 antigen is a 100-105 kD typeI transmembrane glycoprotein that is a member of the immunoglobulin superfamily of proteins, which is also known as Activated leukocyte cell adhesion molecule (ALCAM) in human, SC-1/DM-GRASP/BEN in the chicken, and KG-CAM in the rat. CD166 is a cell adhesion molecule that binds to CD6. CD166 involved in neurite extension by neurons via heterophilic and homophilic interactions.
REFERENCES:1) Degen W.G., et al., 1998, Am. J. Pathol. 152:805-813.
2) Skonier J.E., et al., 1996, Biochemistry 35:12287-12291.
3) Bajorath J., et al., 1995, Protein Sci. 4:1644-1647.

FOR RESEARCH USE ONLY.

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