AKT2 Monoclonal Antibody [8G3B6], KO Validated Cat. No.: 18-206

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psi-iconSpecifications
HOST SPECIES:Mouse
SPECIES REACTIVITY: Human, Monkey, Mouse, Rat
IMMUNOGEN: Recombinant protein of human AKT2
TESTED APPLICATIONS: ChIP, ICC, IF, IHC, IP, WB
APPLICATIONS: WB: ,1:500 - 1:2000

IHC: ,1:50 - 1:100

ICC: ,1:50 - 1:200

IF: ,1:50 - 1:100

IP: ,1:20 - 1:50

ChIP: ,1:20 - 1:100
POSITIVE CONTROL:1) 293T
PREDICTED MOLECULAR WEIGHT: Observed: 60kDa
psi-iconAdvanced Validation
VALIDATION: Antibody is Knockout validated.

psi-iconProperties
PURIFICATION:Affinity purification
CLONALITY:Monoclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
STORAGE CONDITIONS:Store at -20˚C. Avoid freeze / thaw cycles.

psi-iconAdditional Info
OFFICIAL SYMBOL:AKT2
ALTERNATE NAMES:rac protein kinase beta, Murine thymoma viral (v-akt) homolog-2, RAC-BETA, PRKBB, PKBBETA, HGNC:392, v-akt murine thymoma viral oncogene homolog 2, AKT2, PKBB, HIHGHH
GENE ID:208
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins.

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