AHR Polyclonal Antibody, KO Validated Cat. No.: 18-223

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Human, Mouse, Rat
IMMUNOGEN: Recombinant fusion protein containing a sequence corresponding to amino acids 619-848 of human AHR (NP_001612.1).
TESTED APPLICATIONS: IHC, WB
APPLICATIONS: WB: ,1:200 - 1:2000

IHC: ,1:50 - 1:200
POSITIVE CONTROL:1) HeLa
PREDICTED MOLECULAR WEIGHT: Observed: 125kDa
psi-iconAdvanced Validation
VALIDATION: Antibody is Knockout validated.

psi-iconProperties
PURIFICATION:Affinity purification
CLONALITY:Polyclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
STORAGE CONDITIONS:Store at -20˚C. Avoid freeze / thaw cycles.

psi-iconAdditional Info
OFFICIAL SYMBOL:AHR
ALTERNATE NAMES:AHR, bHLHe76
GENE ID:196
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes.

ANTIBODIES FOR RESEARCH USE ONLY.

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