Specifications
| HOST SPECIES: | Goat |
| SPECIES REACTIVITY: |
Human, Mouse |
| IMMUNOGEN: |
The immunogen for this antibody is: C-EIQKNKPRNDDIFK |
| TESTED APPLICATIONS: |
ELISA, WB |
| APPLICATIONS: |
Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Approx 38kDa band observed in Human and Mouse Liver lysates (calculated MW of 41.1kDa according to Human NP_000676.1 and 40.9kDa according to Mouse NP_796296.1) Additional bands of unknown identity were also observed at 45 and 75kDakDa and were successfully blocked by incubation with the immunizing peptide. Recommended concentration: 0.1-0.3ug/ml. Primary incubation 1 hour at room temperature. |
| SPECIFICITY: |
All reported variants represent identical protein (NP_000676.1, NP_004826.2, NP_033611.1, NP_114038.1 and NP_114438.1). |
| POSITIVE CONTROL: | 1) Cat. No. 1404 - Mouse Liver Tissue Lysate |
Properties
| PURIFICATION: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| CLONALITY: | Polyclonal |
| CONJUGATE: | Unconjugated |
| PHYSICAL STATE: | Liquid |
| BUFFER: | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20°C. Minimize freezing and thawing. |
| CONCENTRATION: | 500 ug/mL |
| STORAGE CONDITIONS: | Aliquot and store at -20˚C. Minimize freezing and thawing. |
Additional Info
| OFFICIAL SYMBOL: | AGTR1 |
| ALTERNATE NAMES: | AGTR1, AT1, angiotensin II receptor, type 1 , AG2S, AGTR1A, AGTR1B, AT1B, AT2R1, AT2R1A, AT2R1B, HAT1R, angiotensin receptor 1, angiotensin receptor 1B, type-1B angiotensin II receptor |
| ACCESSION NO.: | NP_000676.1, NP_004826.2, NP_033611.1, NP_114038.1, NP_114438.1 |
| PROTEIN GI NO.: | 4501997 |
| GENE ID: | 185 |
Background and References
| REFERENCES: | 1) Wang M, Jiang C, Wang C, Yao Q. The Role of brain angiotensinergic AT(1) receptor in the carbachol-induced natriuresis and expression of nNOS in the Locus Coeruleus (LC) and proximal convoluted tubule (PCT). Physiol Res. 2006 Aug 22; |
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