AGTR1 Antibody Cat. No.: 14-808

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Human
IMMUNOGEN: A synthetic peptide of human AGTR1
TESTED APPLICATIONS: Flow, IF, IHC, WB
APPLICATIONS: WB: ,1:500 - 1:1000

IHC: ,1:50 - 1:100

IF: ,1:20 - 1:50

Flow: ,1:20 - 1:50
POSITIVE CONTROL:1) U-87MG
 2) PC-12
PREDICTED MOLECULAR WEIGHT: Observed: 56kDa

psi-iconProperties
PURIFICATION:Affinity purification
CLONALITY:Polyclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:PBS with 0.02% sodium azide, pH7.3.
STORAGE CONDITIONS:Store at 4˚C. Avoid freeze / thaw cycles.

psi-iconAdditional Info
OFFICIAL SYMBOL:AGTR1
ALTERNATE NAMES:AGTR1 Antibody: AT1, AG2S, AT1B, AT1R, AT1AR, AT1BR, AT2R1, HAT1R, AGTR1B, AGTR1A, AT2R1B, Type-1 angiotensin II receptor, AT1
GENE ID:185
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene.

ANTIBODIES FOR RESEARCH USE ONLY.

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