AFP Antibody [F3B0] Cat. No.: 14-176

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psi-iconSpecifications
HOST SPECIES:Mouse
SPECIES REACTIVITY: Human, Mouse, Rat
IMMUNOGEN: Recombinant protein of human AFP
TESTED APPLICATIONS: IF, IHC, WB
APPLICATIONS: WB: ,1:500 - 1:2000

IHC: ,1:50 - 1:200

IF: ,1:50 - 1:200
POSITIVE CONTROL:1) HepG2
 2) human plasma
 3) SH-SY5Y
 4) mouse plasma
 5) mouse liver
 6) mouse kidney
PREDICTED MOLECULAR WEIGHT: Observed: 69kDa

psi-iconProperties
PURIFICATION:Affinity purification
CLONALITY:Monoclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
STORAGE CONDITIONS:Store at -20˚C. Avoid freeze / thaw cycles.

psi-iconAdditional Info
OFFICIAL SYMBOL:AFP
ALTERNATE NAMES:AFP Antibody: FETA, HPAFP, Alpha-fetoprotein, Alpha-1-fetoprotein
GENE ID:174
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

ANTIBODIES FOR RESEARCH USE ONLY.

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