AFP Antibody Cat. No.: XW-7017

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psi-iconSpecifications
HOST SPECIES:Chicken
SPECIES REACTIVITY: Human
IMMUNOGEN: 180-420
TESTED APPLICATIONS: WB
APPLICATIONS: AFP antibody can be used for the detection of AFP by Western blot, may also work for IHC and ICC.
PREDICTED MOLECULAR WEIGHT: 68.7 kDa (calculated)

psi-iconProperties
PURIFICATION:Antigen affinity-purified
CLONALITY:Polyclonal
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:Phosphate-Buffered Saline. No preservatives added.
CONCENTRATION:1 mg/mL
STORAGE CONDITIONS:AFP antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

psi-iconAdditional Info
OFFICIAL SYMBOL:AFP
ALTERNATE NAMES:HPAFP, Alpha-fetoprotein, Alpha-1-fetoprotein, FETA, HPAFP,
ACCESSION NO.:NP_001125.1
PROTEIN GI NO.:4501989
GENE ID:174
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:α-1-fetoprotein. α-fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. α-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of α-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the α-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. α-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of α-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
REFERENCES:1) Gabant, P., Forrester, L., Nichols, J., Van Reeth, T., De Mees, C., Pajack, B., Watt, A., Smitz, J., Alexandre, H., Szpirer, C., Szpirer, J. Alpha-fetoprotein, the major fetal serum protein, is not essential for embryonic development but is required for female fertility. Proc. Nat. Acad. Sci. 99: 12865-12870, 2002.

ANTIBODIES FOR RESEARCH USE ONLY.

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