HOST SPECIES: | Rabbit |
SPECIES REACTIVITY: | Human, Mouse, Rat |
IMMUNOGEN: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-136 of human Adiponectin Receptor 1 (NP_057083.2). |
TESTED APPLICATIONS: | IF, WB |
APPLICATIONS: | WB: ,1:500 - 1:2000 IF: ,1:50 - 1:200 |
POSITIVE CONTROL: | 1) BT-474 |
2) Mouse skeletal muscle | |
PREDICTED MOLECULAR WEIGHT: | Observed: 38kDa |
PURIFICATION: | Affinity purification |
CLONALITY: | Polyclonal |
ISOTYPE: | IgG |
CONJUGATE: | Unconjugated |
PHYSICAL STATE: | Liquid |
BUFFER: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
STORAGE CONDITIONS: | Store at -20˚C. Avoid freeze / thaw cycles. |
OFFICIAL SYMBOL: | ADIPOR1 |
ALTERNATE NAMES: | AdipoR1; CGI-45 |
GENE ID: | 51094 |
USER NOTE: | Optimal dilutions for each application to be determined by the researcher. |
BACKGROUND: | This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene. |
ANTIBODIES FOR RESEARCH USE ONLY.
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