This recombinant protein can be used for WB. For research use only.
Properties
PURITY:
>85% as determined by SDS-PAGE.
PREDICTED MOLECULAR WEIGHT:
71.6 kDa
PHYSICAL STATE:
Lyophilized
BUFFER:
50 mM Tris, 150 mM NaCl, 20 mM CaCl2, pH7.5
STORAGE CONDITIONS:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Additional Info
ALTERNATE NAMES:
ADAM8, MS2, CD156a
ACCESSION NO.:
AAI15405.1
OFFICIAL SYMBOL:
ADAM8
GENE ID:
101
Background and References
BACKGROUND:
Disintegrin and metalloproteinase domain-containing protein 8 is also known as ADAM8, Cell surface antigen MS2 and CD antigen CD156a, which belongs to the ADAM (a disintegrin and metalloprotease domain) family. ADAM family play a fundamental role in diverse processes such as asthma, development, angiogenesis and cancer through their activities in cell adhesion/fusion, membrane protein shedding, and signal transduction. ADAM8 / CD156a contains 1 disintegrin domain, 1 EGF-like domain and 1 peptidase M12B domain. ADAM8 / MS2 / CD156a is expressed on neutrophils and monocytes. ADAM8 / MS2 possible involvement in extravasation of leukocytes.
REFERENCES:
1) Yoshiyama K., et al., 1997, Genomics 41 (1): 56–62.
2) Hall T., et al., 2012, Acta Crystallogr. F 68:616-621.
Specifications
