ADAM8 Recombinant Protein Cat. No.: 96-013

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psi-iconSpecifications
SPECIES:Human
SOURCE SPECIES:HEK293 cells
SEQUENCE:Ile 17 - Leu 665
FUSION TAG:His Tag
TESTED APPLICATIONS:WB
APPLICATIONS:This recombinant protein can be used for WB. For research use only.
psi-iconProperties
PURITY:>85% as determined by SDS-PAGE.
PREDICTED MOLECULAR WEIGHT:71.6 kDa
PHYSICAL STATE:Lyophilized
BUFFER:50 mM Tris, 150 mM NaCl, 20 mM CaCl2, pH7.5
STORAGE CONDITIONS:Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
psi-iconAdditional Info
ALTERNATE NAMES:ADAM8, MS2, CD156a
ACCESSION NO.:AAI15405.1
OFFICIAL SYMBOL:ADAM8
GENE ID:101
psi-iconBackground and References
BACKGROUND:Disintegrin and metalloproteinase domain-containing protein 8 is also known as ADAM8, Cell surface antigen MS2 and CD antigen CD156a, which belongs to the ADAM (a disintegrin and metalloprotease domain) family. ADAM family play a fundamental role in diverse processes such as asthma, development, angiogenesis and cancer through their activities in cell adhesion/fusion, membrane protein shedding, and signal transduction. ADAM8 / CD156a contains 1 disintegrin domain, 1 EGF-like domain and 1 peptidase M12B domain. ADAM8 / MS2 / CD156a is expressed on neutrophils and monocytes. ADAM8 / MS2 possible involvement in extravasation of leukocytes.
REFERENCES:1) Yoshiyama K., et al., 1997, Genomics 41 (1): 56–62.
2) Hall T., et al., 2012, Acta Crystallogr. F 68:616-621.

FOR RESEARCH USE ONLY.

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