ADAM19 Antibody Cat. No.: 43-479

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psi-iconSpecifications
HOST SPECIES:Goat
SPECIES REACTIVITY: Human
HOMOLOGY: Expected Species Reactivity based on sequence homology: Dog, Pig, Cow
IMMUNOGEN: The immunogen for this antibody is: KIQCQSSEARPLESN
TESTED APPLICATIONS: ELISA, IHC, WB
APPLICATIONS: Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Approx 125kDa band observed in Human Spleen lysates (calculated MW of 101kDa according to NP_150377.1). The observed molecular weight corresponds to the glycosylated form. Recommended concentration: 0.1-0.3ug/ml.Immunohistochemistry:Paraffin embedded Human Spleen. Recommended concentration: 5ug/ml.
PREDICTED MOLECULAR WEIGHT: Approx 125kDa

psi-iconProperties
PURIFICATION:Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
CLONALITY:Polyclonal
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
CONCENTRATION:500 ug/mL
STORAGE CONDITIONS:Aliquot and store at -20˚C. Minimize freezing and thawing.

psi-iconAdditional Info
OFFICIAL SYMBOL:ADAM19
ALTERNATE NAMES:ADAM19, ADAM metallopeptidase domain 19, MADDAM, MLTNB, ADAM 19, a disintegrin and metalloproteinase domain 19 (meltrin beta), disintegrin and metalloproteinase domain-containing protein 19, meltrin beta, meltrin-beta, metalloprotease and disintegrin dendritic antigen marker
ACCESSION NO.:NP_150377.1
PROTEIN GI NO.:15451844
GENE ID:8728
psi-iconBackground and References
REFERENCES:1) Yoshikawa A, Aizaki Y, Kusano K, Kishi F, Susumu T, Iida S, Ishiura S, Nishimura S, Shichiri M, Senbonmatsu T.The (pro)renin receptor is cleaved by ADAM19 in the Golgi leading to its secretion into extracellular space.

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