ACVRL1 Antibody Cat. No.: 18-157

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psi-iconSpecifications
HOST SPECIES:Rabbit
SPECIES REACTIVITY: Human, Mouse, Rat
IMMUNOGEN: Recombinant protein of human ACVRL1
TESTED APPLICATIONS: WB
APPLICATIONS: WB: ,1:500 - 1:2000
POSITIVE CONTROL:1) SH-SY5Y
 2) HL-60
 3) MCF7
 4) Jurkat
 5) Mouse lung
 6) Mouse heart
PREDICTED MOLECULAR WEIGHT: Observed: 65kDa

psi-iconProperties
PURIFICATION:Affinity purification
CLONALITY:Polyclonal
ISOTYPE:IgG
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
STORAGE CONDITIONS:Store at -20˚C. Avoid freeze / thaw cycles.

psi-iconAdditional Info
OFFICIAL SYMBOL:ACVRL1
ALTERNATE NAMES:ACVRL1, HHT, ALK1, HHT2, ORW2, SKR3, ALK-1, ACVRLK1, activin A receptor type II-like 1, Activin A receptor, type II-like kinase 1
GENE ID:94
USER NOTE:Optimal dilutions for each application to be determined by the researcher.
psi-iconBackground and References
BACKGROUND:This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.

ANTIBODIES FOR RESEARCH USE ONLY.

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