| SPECIES: | Human |
| SOURCE SPECIES: | E. coli |
| SEQUENCE: | aa. 1-375 |
| TESTED APPLICATIONS: | ELISA, MS, WB |
| APPLICATIONS: | This recombinant protein can be used for WB, ELISA, MS. |
| BIOLOGICAL ACTIVITY: | N/A |
Specifications| PURITY: | >95% |
| PREDICTED MOLECULAR WEIGHT: | 41.8 kDa (Calculated) |
| PHYSICAL STATE: | Liquid |
| BUFFER: | 10 mM Tris, pH 8.0, 0.1% Triton X-100, 0.002% NaN3 |
| STORAGE CONDITIONS: | Store in working aliquots at -70˚C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature. |
| ALTERNATE NAMES: | ACT, ACTG, BRWS2, DFNA20, DFNA26, HEL-176, ACTB, Actin, cytoplasmic 2, Gamma-actin |
| ACCESSION NO.: | NP_001605 |
| PROTEIN GI NO.: | 4501887 |
| OFFICIAL SYMBOL: | ACTG1 |
| GENE ID: | 71 |
| BACKGROUND: | Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, α, β and γ have been identified. The α actins are found in muscle tissues and are a major constituent of the contractile apparatus. The β and γ actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, γ 1, encoded by this gene, is a cytoplasmic actin found in nonmuscle cells. FUNCTION: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. SUBUNIT: Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. |
| REFERENCES: | 1) Cheng,C. and Sharp,P.A.: RNA polymerase II accumulation in the promoter-proximal region of the dihydrofolate reductase and gamma-actin genes. Mol. Cell. Biol. 23 (6), 1961-1967 (2003) |
FOR RESEARCH USE ONLY.
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