ACTG1 Recombinant Protein Cat. No.: XW-RP3002

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psi-iconSpecifications
SPECIES:Human
SOURCE SPECIES:E. coli
SEQUENCE:aa. 1-375
TESTED APPLICATIONS:ELISA, MS, WB
APPLICATIONS:This recombinant protein can be used for WB, ELISA, MS.
BIOLOGICAL ACTIVITY: N/A
psi-iconProperties
PURITY:>95%
PREDICTED MOLECULAR WEIGHT:41.8 kDa (Calculated)
PHYSICAL STATE:Liquid
BUFFER:10 mM Tris, pH 8.0, 0.1% Triton X-100, 0.002% NaN3
STORAGE CONDITIONS:Store in working aliquots at -70˚C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
psi-iconAdditional Info
ALTERNATE NAMES:ACT, ACTG, BRWS2, DFNA20, DFNA26, HEL-176, ACTB, Actin, cytoplasmic 2, Gamma-actin
ACCESSION NO.:NP_001605
PROTEIN GI NO.:4501887
OFFICIAL SYMBOL:ACTG1
GENE ID:71
psi-iconBackground and References
BACKGROUND:Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, α, β and γ have been identified. The α actins are found in muscle tissues and are a major constituent of the contractile apparatus. The β and γ actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, γ 1, encoded by this gene, is a cytoplasmic actin found in nonmuscle cells.

FUNCTION: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

SUBUNIT: Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others.
REFERENCES:1) Cheng,C. and Sharp,P.A.: RNA polymerase II accumulation in the promoter-proximal region of the dihydrofolate reductase and gamma-actin genes. Mol. Cell. Biol. 23 (6), 1961-1967 (2003)

FOR RESEARCH USE ONLY.

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