ABCA2 Antibody Cat. No.: 46-787

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psi-iconSpecifications
HOST SPECIES:Goat
SPECIES REACTIVITY:
IMMUNOGEN: ABCA2 antibody was raised against a 14 amino acid synthetic peptide near the internal region of ABCA2.
TESTED APPLICATIONS: ELISA
APPLICATIONS: ELISA: antibody detection limit dilution 1:2000. Western Blot: Preliminary experiments gave an approx 35kDa band in Human Brain (Amygdala, Frontal Cortex, Hippocampus and Substantia Nigra) lysates after 0.3μg/ml antibody staining. Please note that currently we cannot find an explanation in the literatu
SPECIFICITY: This antibody is expected to recognize both reported isoforms (NP_001597.2; NP_997698.1).

psi-iconProperties
PURIFICATION:ABCA2 antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
CLONALITY:Polyclonal
CONJUGATE:Unconjugated
PHYSICAL STATE:Liquid
BUFFER:ABCA2 antibody is supplied in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.
CONCENTRATION:500 ug/mL
STORAGE CONDITIONS:Aliquot and store at -20˚C. Minimize freezing and thawing.

psi-iconAdditional Info
OFFICIAL SYMBOL:ABCA2
ALTERNATE NAMES:ABCA2, ATP-binding cassette, sub-family A (ABC1), member 2, ABC2, MGC129761, sub-family A, OTTHUMP00000064733, KIAA1062
ACCESSION NO.:NP_001597.2, NP_997698.1
PROTEIN GI NO.:45446740
GENE ID:20
psi-iconBackground and References
REFERENCES:1) Mace S, Cousin E, Ricard S, Genin E, Spanakis E, Lafargue-Soubigou C, Genin B, Fournel R, Roche S, Haussy G, Massey F, Soubigou S, Brefort G, Benoit P, Brice A, Campion D, Hollis M, Pradier L, Benavides J, Deleuze JF ABCA2 is a strong genetic risk factor for early-onset Alzheimer's disease Neurobiol Dis. 2005 Feb;18(1):119-25

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