Datasheet

ABCA2 Antibody
CATALOG NUMBER: 46-787

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Specifications
Properties
Additional Info
Background

Specifications

SPECIES REACTIVITY:
TESTED APPLICATIONS:ELISA
APPLICATIONS:ELISA: antibody detection limit dilution 1:2000. Western Blot: Preliminary experiments gave an approx 35kDa band in Human Brain (Amygdala, Frontal Cortex, Hippocampus and Substantia Nigra) lysates after 0.3μg/ml antibody staining. Please note that currently we cannot find an explanation in the literatu
SPECIFICITY:This antibody is expected to recognize both reported isoforms (NP_001597.2; NP_997698.1).
IMMUNOGEN:ABCA2 antibody was raised against a 14 amino acid synthetic peptide near the internal region of ABCA2.
HOST SPECIES:Goat

Properties

PURIFICATION:ABCA2 antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
PHYSICAL STATE:Liquid
BUFFER:ABCA2 antibody is supplied in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin.
CONCENTRATION:500 ug/mL
STORAGE CONDITIONS:Aliquot and store at -20˚C. Minimize freezing and thawing.
CLONALITY:Polyclonal
CONJUGATE:Unconjugated

Additional Info

ALTERNATE NAMES:ABCA2, ATP-binding cassette, sub-family A (ABC1), member 2, ABC2, MGC129761, sub-family A, OTTHUMP00000064733, KIAA1062
ACCESSION NO.:NP_001597.2, NP_997698.1
PROTEIN GI NO.:45446740
OFFICIAL SYMBOL:ABCA2
GENE ID:20

Background

REFERENCES: 1) Mace S, Cousin E, Ricard S, Genin E, Spanakis E, Lafargue-Soubigou C, Genin B, Fournel R, Roche S, Haussy G, Massey F, Soubigou S, Brefort G, Benoit P, Brice A, Campion D, Hollis M, Pradier L, Benavides J, Deleuze JF ABCA2 is a strong genetic risk factor for early-onset Alzheimer's disease Neurobiol Dis. 2005 Feb;18(1):119-25

For Research Use Only