4‑1BB Ligand Recombinant Protein Cat. No.: 96-967

Availability: In stock

$0.00

 Price Options

$0.00
psi-iconSpecifications
SPECIES:Mouse
SOURCE SPECIES:HEK293 cells
SEQUENCE:Arg 104 - Glu 309
FUSION TAG:Fc Tag
TESTED APPLICATIONS:ELISA, WB
APPLICATIONS:This recombinant protein can be used for E, WB. For research use only.
BIOLOGICAL ACTIVITY: Measured by its binding ability in a functional ELISA. Immobilized Mouse 4-1BB, His Tag at 0.5 ug/mL (100 ul/well),can bind Mouse 4-1BB Ligand , Fc Tag with a linear of 0.1-3 ng/mL (QC tested).
psi-iconProperties
PURITY:>95% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.
PREDICTED MOLECULAR WEIGHT:49 kDa
PHYSICAL STATE:Lyophilized
BUFFER:Tris with Glycine, Arginine and NaCl, pH7.5
STORAGE CONDITIONS:Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
psi-iconAdditional Info
ALTERNATE NAMES:#REF!
ACCESSION NO.:NP_033430
OFFICIAL SYMBOL:4‑1BB Ligand
GENE ID:21950
psi-iconBackground and References
BACKGROUND:Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9. 4-1BBL is the high affinity ligand of 4-1BB. 4-1BBL induces the proliferation of activated peripheral blood T-cells. Also, 4-1BBL may have a role in activation-induced cell death (AICD). Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages. As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.
REFERENCES:1) Won E.Y., et al., 2010, J. Biol. Chem. 285:9202-9210.
2) Alderson M.R., et al., 1994, Eur. J. Immunol. 24:2219-2227.

FOR RESEARCH USE ONLY.

For additional information, visit ProSci's Terms & Conditions Page.