| SPECIES: | Human |
| SOURCE SPECIES: | E. coli |
| SEQUENCE: | Arg71-Glu254 |
| FUSION TAG: | C-6 His tag |
| TESTED APPLICATIONS: | |
| APPLICATIONS: | This recombinant protein can be used for biological assays. For research use only. |
Specifications| PURITY: | Greater than 95% as determined by reducing SDS-PAGE. Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test. |
| PREDICTED MOLECULAR WEIGHT: | 20.6 kD |
| PHYSICAL STATE: | Lyophilized |
| BUFFER: | Lyophilized from a 0.2 um filtered solution of 20mM PB，150mM NaCl,pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. |
| STORAGE CONDITIONS: | Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7˚C for 2-7 days. Aliquots of reconstituted samples are stable at -20˚C for 3 months. |
| ALTERNATE NAMES: | Tumor necrosis factor ligand superfamily member 9, 4-1BB ligand, 4-1BBL, TNFSF9., TNFSF9, CD137L |
| ACCESSION NO.: | P41273 |
| PROTEIN GI NO.: | 578833707 |
| OFFICIAL SYMBOL: | TNFSF9 |
| GENE ID: | 8744 |
| BACKGROUND: | Tumor necrosis factor ligand superfamily member 9, also known as 4-1BBL, is a member of the the tumor necrosis factor family. It is a 254 amino acids cytokine that is expressed in brain, placenta, lung, skeletal muscle and kidney. TNFSF9 has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells, and is thought to be involved in T cell-tumor cell interaction. |
FOR RESEARCH USE ONLY.
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