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High Performance Antibodies...and More

COVID-19

SARS-CoV-2 Variants

Spike antibodies and recombinant proteins representing key mutations such as P681H, N501Y, K417N, K417T, and E484K.

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SARS-CoV-2 Antibody Pairs

Capture and detection antibodies against SARS-CoV-2 nucleocapsid and spike proteins.

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SARS-CoV-2 Antibodies Validated with Patient Samples

Antibodies against structural and nonstructural proteins validated with the SARS-CoV-2 virus.

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ACE-2 Antibodies

ACE2, TMPRSS2, and Furin antibodies and recombinant proteins.

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SARS CoV Small Molecule Inhibitors

Small molecule inhibitors for viral entry, proteases, RdRps … and more.

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SARS-CoV-2 Accessory Factors Reagents

Variant and wild type proteins to spike, envelope, membrane, nucleocapsid, ORFs, ACE2 … and more.

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Viral Infectious Diseases Research Reagents

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SARS-CoV-2 Research Reagents

ProSci enables advancements in COVID-19 research with its broad catalog of antibodies, proteins … and more.

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Immune Checkpoint

VISTA

VISTA is an immunoregulatory receptor that inhibits the T-cell response. May promote embryonic stem cell differentiation.

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TMIGD2

TMIGD2 plays a role in cell migration, cell-cell interation, and angiogenesis. Enhances cytokine production and T-cell proliferation.

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TIM-3

TIM3 (HAVCR2) is a specific T helper type 1 (Th1) cell surface marker. Promotes immune tolerance.

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TIGIT

TIGIT binding to PVR causes increased secretion of IL-10 and decreased secretion of IL-12B. Suppresses T-cell activation.

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PD-L2

PD-L2 inhibits T-cell proliferation by blocking cell cycle and cytokine production upon binding to PD-1.

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PD-L1

PD-L1 (CD274) is a strong immunosuppressor, inhibiting cytokine production and T-cell activation upon binding to PD-1.

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PD-1

PD-1 receptor induces and maintains immune tolerance to self. May play a role in pro-B-cell differentiation.

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LIGHT

LIGHT (TNFSF14) is a cytokine which stimulates T-cell proliferation and IFNG production.

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LAG-3

LAG3 of the immunoglobulin superfamily mediates immune tolerance, delivering inhibitory signals upon ligand binding.

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CTLA-4

CTLA4 (CD152) of the immunoglobulin superfamily inhibits T-cells; soluble monomer or membrane homodimer.

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CD80

When activated by CD28 or CTLA-4, CD80 induces T-cell proliferation and cytokine production.

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B7-H3

B7-H3 (CD276) is only expressed in tumors; thought to aid regulation of T-cell-mediated immune response.

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Immune Checkpoint Research Reagents

High performance mouse monoclonal and llama single domain recombinant antibodies to top immune checkpoint targets.

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Explore Our New Products

ProSci is continuously enabling researchers worldwide through the development of high performance antibodies … and more.

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    ProSci was the first to develop antibodies to newly emerged influenza strains of avian and swine origin. Browse H5N1 and H7N9 avian and seasonal flu, H1N1 swine and season flu, H3N2, and influenza A and B reagents.

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