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Primary Antibodies
tel Antibody
Background
Tel encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in the protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.
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Description
Left: Western blot analysis of Tel expression in HepG2 (A), Raji (B) and 293T (C) cell lysates using anti-Tel.
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Purification
Rabbit IgG is purified by Protein A/G affinity chromatography method.
Clonality / Clone
This is a polyclonal antibody.
Host
tel antibody was raised in rabbit.
Please use anti-rabbit IgG secondary antibodies.
Immunogen
tel antibody was produced in rabbits immunized with a synthetic peptide corresponding to a region of human ETV6.
Application
tel antibody can be used for Western blot at a suggested dilution of 1 μg/ml in 5% skim milk / PBS buffer, and HRP conjugated anti Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody. The protein size is 452 amino acids.
Tested Application
WB
Buffer
Antibody is supplied in PBS buffer with 2% sucrose. Product may ship lyophilized. To reconstitute add 100μl of distilled water making the final concentration 1 mg/ml.
Storage
tel antibody is supplied in PBS buffer containing 0.02% sodium azide. For longer periods of storage, store at -20ºC. Avoid repeat freeze-thaw cycle.
Positive Control
- Cat. No. 1211 - HepG2 Cell Lysate
- Cat. No. 1207 - Raji Cell Lysate
- Cat. No. 1210 - 293 Cell Lysate
Species Reactivity
H
Protein Accession Number
NP_001978
Molecular Weight
50 kDa
Short Description
Anti-tel
This product belongs to the following categories:
Related Products
References- Lopez, R.G. et al., (2003) J. Biol. Chem. 278 (42), 41316-41325.
Datasheet 0802-W
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