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Primary Antibodies
ZIP11 Antibody
Background
ZIP11, also known as Slc39A11, is a member of the broader ZIP family of multi-transmembrane domain metal ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Members of the ZIP family generally transport metal ions from the cell exterior or lumen of intracellular organelles into the cytoplasm, as opposed to the ZnT (SLC30) family of zinc transporters that serve to reduce intracellular zinc availability by promoting zinc efflux from cells or into intracellular vesicles. At least three isoforms of ZIP11 are known to exist. This antibody will not cross-react with the zinc transporter ZIP10.
Additional Names
ZIP11, Solute carrier family 39 member a11, Slc39a11
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Description
Left: Western blot analysis of ZIP11 in mouse kidney tissue lysate with ZIP11 antibody at (A) 1 and (B) 2 μg/ml.
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Source
ZIP11 antibody was raised against a 15 amino acid peptide near the center of the human ZIP11.
Purification
Affinity chromatography purified via peptide column
Clonality / Clone
This is a polyclonal antibody.
Host
ZIP11 antibody was raised in rabbit.
Please use anti-rabbit secondary antibodies.
Application
ZIP11 antibody can be used for detection of ZIP11 by Western blot at 1 – 2 μg/ml.
Tested Application
E, WB
Buffer
Antibody is supplied in PBS containing 0.02% sodium azide.
Blocking Peptide
Cat.No. 5001P - ZIP11 Peptide
Storage
ZIP11 antibody can be stored at 4˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Positive Control
- Cat. No. 1405 - Mouse Kidney Tissue Lysate
Species Reactivity
H, M, R
Protein GI Number
119609513
Protein Accession Number
EAW89107
Short Description
Solute carrier family 39 member a11
This product belongs to the following categories:
Related Products
References- Eide DJ. The SLC39 family of metal ion transporters. Pflugers Arch. 2004; 447:796-800.
- Taylor KM and Nicohlson RI. The LZT proteins; the LIV-1 subfamily of zinc transporters. Biochim. Biophys. Acta. 2003; 1611:16-30.
- Liuzzi JP and Cousins RJ. Mammalian zinc transporters. Annu. Rev. Nutr. 2004; 24:151-72.
Datasheet 09-01W
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