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Primary Antibodies
ZBTB1 Antibody
Background
ZBTB1 is a zinc finger protein that also contains BTB (BR-C, ttk and bab) domain. While little is known about this protein or the related protein ZBTB2, its expression is known to be down-regulated in human bronchial epithelial cells in response to the presence of Vanadium. Recently, expression of variant ZBTB1 protein has been associated with increased age-related macular degeneration. At least two isoforms of ZBTB1 are known to exist. This ZBTB1 antibody will not cross-react with ZBTB2.
Additional Names
ZBTB1, Zinc finger and BTB domain-containing protein 1, ZBTB
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Description
Left: Western blot analysis of ZBTB1 in HepG2 lysate with ZBTB1 antibody at (A) 1 and (B) 2 μg/ml.
Below: Immunohistochemistry of ZBTB1 in mouse brain tissue with ZBTB1 antibody at 2.5 μg/ml.
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Other Product Images
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Source
ZBTB1 antibody was raised against a 14 amino acid peptide near the center of human ZBTB1.
Purification
Affinity chromatography purified via peptide column
Clonality / Clone
This is a polyclonal antibody.
Host
ZBTB1 antibody was raised in rabbit.
Please use anti-rabbit secondary antibodies.
Application
ZBTB1 antibody can be used for detection of ZBTB1 by Western blot at 1 – 2 μg/ml.
Tested Application
E, WB, IHC
Buffer
Antibody is supplied in PBS containing 0.02% sodium azide.
Blocking Peptide
Cat.No. 4951P - ZBTB1 Peptide
Storage
ZBTB1 antibody can be stored at 4˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Positive Control
- Cat. No. 1211 - HepG2 Cell Lysate
Species Reactivity
H, M, R
Protein GI Number
29792103
Protein Accession Number
AAH50719
Short Description
Zinc finger and BTB domain-containing protein 1
This product belongs to the following categories:
Related Products
References- Strausberg RL, Feingold EA, Grouse LH, et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. USA 2002; 99:16899-903.
- Li Z, Stonehuerner J, Devlin RB, et al. Discrimination of Vanadium from Zinc using gene profiling in human bronchial epithelial cells. Envir. Health Perspect. 2005; 113:1747-54.
- Zhang H, Morrison MA, Dewan A, et al. The NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration. BMC Med. Genet. 2008; 9:51.
Datasheet 09-01W
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