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Primary Antibodies
WAS Antibody
Background
FUNCTION: Effector protein for Rho-type GTPases, providing a link with the Arp2/3 complex that regulates the structure and dynamics of the actin cytoskeleton. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function.
DISEASE: Defects in WAS are the cause of isolated X-linked thrombocytopenia (XLT) [MIM:313900]. XLT is clinically mild with small platelets and subclinical leukocyte abnormalities.
Additional Names
WiskottAldrich syndrome protein, WASp
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Description
Left: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.
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Location
The gene that codes for this protein is at chromosomal location Xp11.4-p11.21.
Purification
Immunoaffinity Purified
Clonality / Clone
This is a polyclonal antibody.
Host
WAS antibody was raised in chicken.
Please use anti-chicken secondary antibodies.
Immunogen
313-425
Application
WAS antibody can be used for the detection of Wiskott-Aldrich syndrome protein by Western Blot.
Tested Application
WB
Buffer
Phosphate-Buffered Saline. No preservatives added.
Storage
WAS antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Species Reactivity
H
Protein GI Number
4507909
Protein Accession Number
NP_000368.1
Molecular Weight
52.8 kDa (calculated)
Short Description
Wiskott-Aldrich syndrome protein, WASp
This product belongs to the following categories:
Datasheet 0801-W
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