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XW-7675


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GeneDireX Molecular Weight Marker


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Primary Antibodies

WAS Antibody

Background

FUNCTION: Effector protein for Rho-type GTPases, providing a link with the Arp2/3 complex that regulates the structure and dynamics of the actin cytoskeleton. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function.

DISEASE: Defects in WAS are the cause of isolated X-linked thrombocytopenia (XLT) [MIM:313900]. XLT is clinically mild with small platelets and subclinical leukocyte abnormalities.

Additional Names

WiskottAldrich syndrome protein, WASp

WAS Antibody

Description

Left: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.

Location

The gene that codes for this protein is at chromosomal location Xp11.4-p11.21.

Purification

Immunoaffinity Purified

Clonality / Clone

This is a polyclonal antibody.

Host

WAS antibody was raised in chicken.

Please use anti-chicken secondary antibodies.

Immunogen

313-425

Application

WAS antibody can be used for the detection of Wiskott-Aldrich syndrome protein by Western Blot.

Tested Application

WB

Buffer

Phosphate-Buffered Saline. No preservatives added.

Storage

WAS antibody can be stored at 4˚C for short term (weeks). Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Species Reactivity

H

Protein GI Number

4507909

Protein Accession Number

NP_000368.1

Molecular Weight

52.8 kDa (calculated)

Short Description

Wiskott-Aldrich syndrome protein, WASp

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