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Primary Antibodies
TGFB1 Antibody
Background
TGF-beta-1 is a multifunctional cytokine that belongs to a superfamily of structurally related regulatory proteins, which includes three mammalian TGF-beta isoforms (TGF-beta-1, -beta-2, and -beta-3), activin/inhibins and bone morphogenetic proteins. The most abundant isoform, TGF-beta-1, is a 25kDa homodimer composed of two 12.5kDa subunits joined by disulfide bonds. TGF-beta-1 is a highly conserved molecule - the amino acid sequence between human and mouse differ only by one residue. Although originally defined by its ability to cause anchorage independent cell growth and changes in cell morphology of rat fibroblasts, subsequent research has revealed that TGF-beta is actually a major growth inhibitor for most cell types. It is produced by a wide variety of cell and tissue types during all stages of cell differentiation. TGF-beta-1 sources include platelets, bone and soft tissues such as placenta and kidneys.
Additional Names
TGFB1, CED, DPD1, TGF-BETA-1, TGFB, diaphyseal dysplasia 1, transforming growth factor beta 1
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Description
Left: Immunohistochemistry staining of TGFB1 in spleen (formalin-fixed paraffin-embedded) using TGFB1 antibody.
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Purification
Immunoaffinity Chromatography
Clonality / Clone
This is a polyclonal antibody.
Host
TGFB1 antibody was raised in rabbit.
Please use anti-rabbit secondary antibodies.
Immunogen
TGFB1 antibody was raised against aa 286-293 of TGFB1. (Human)
Application
TGFB1 antibody can be used for detection of TGFB1 by WB (1:200 - 1:1000), ELISA (1:2000 - 1:10000), IF, IHC-parafin (5 μg/ml).
Tested Application
E, WB, IHC, IF
Buffer
TGFB1 antibody is supplied in 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.
Storage
TGFB1 antibody can be stored at 4˚C or -20˚C, Avoid repeated freezing and thawing.
Species Reactivity
Rb
Formulation
Weight: 50 μg
Concentration: 0.5 mg/ml
Short Description
Transforming Growth Factor
This product belongs to the following categories:
Datasheet 09-01W
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