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Peptides
SOCS1 Peptide
Background
SOCS1 (C-Terminus) Peptide
Additional Names
Suppressor of cytokine signaling 1 / JAK-binding protein / JAB
Location
15 amino acids near the carboxy terminus of human SOCS1.
Application
SOCS1 peptide is used for blocking the activity of SOCS1 antibody (Cat. No. 3765). It usually blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37˚C.
Tested Application
Bl
Buffer
PBS containing 0.02% sodium azide
Storage
SOCS1 peptide is supplied as 200 μg/ml, 50 μg/vial, in PBS pH7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide. Store at -20˚C, stable for one year.
Species Reactivity
n/a
Species
H
Short Description
(CT) SOCS1 peptide
This product belongs to the following categories:
Related Products
References- Yoshida H, Matsui T, Yamamoto T, et al. XBP1 mRNA is induced by ATF6 and spliced by IRE1p in response to ER stress to produce a highly active transcription factor. Cell 2001; 107:881-91.
- Calfon M, Zeng H, Urano F, et al. IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature 2002; 415:92-6.
- Haze K, Yoshida H, Yanagi H, et al. Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic stress. Mol. Cell. Biol. 1999; 10:3787-99.
- Little E, Ramakrishnan M, Roy B, et al. The glucose-regulated proteins (GRP78 and GRP94): functions, gene regulation, and applications. Crit. Rev. Eukaryot. Gene Expr. 1994; 4:1-18.
Datasheet 0801-W
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